Disseminated Superficial Porokeratosis with Dermal Amyloid Deposits
نویسندگان
چکیده
Only 6 cases with an association of disseminated superficial porokeratosis with dermal amyloid deposits are reported in the literature. We present the case of a 76-year-old woman who presented with a disseminated superficial porokeratosis. Histological examination revealed amyloid deposits in the upper dermis, which were typed with routine HE stains, Congo red stains and anticytokeratin antibodies (AE1-AE3 and CK5). Positive staining with Congo red and, moreover, with CK5 (a cytokeratin strongly represented in the basal cell layer of the epidermis) indicates an epidermal origin of this protein.
منابع مشابه
[Localized cutaneous amyloidosis secondary to porokeratosis: a retrospective histopathologic study of 30 patients].
INTRODUCTION Porokeratosis is a rare disorder of keratinization. The presence of amyloid deposits has been observed in inflammatory and tumoral skin diseases. OBJECTIVES The aim of this study was to determine the frequency of cutaneous amyloidosis in histology samples from various types of porokeratosis diagnosed in our department from 1988 to 2005. MATERIAL AND METHODS Thirty patients were...
متن کاملSecondary cutaneous amyloidosis in disseminated superficial porokeratosis: a case report.
Disseminated superficial porokeratosis (DSP) is a rare cause of secondary cutaneous amyloidosis. An 83-year-old male patient showed an increase in both size and number of DSP lesions after contracting pulmonary tuberculosis. The DSP lesions of the patient consisted of numerous annular eruptions on both sun-exposed and sun-protected areas, which occurred over a period of 20 years. Multiple skin ...
متن کاملCoexistence of Disseminated Superficial Actinic Porokeratosis and Ptychotropica Porokeratosis
Porokeratosis (PK) is an uncommon disorder of epidermal keratinization characterized by annular plaques with an atrophic center surrounded by a raised, keratotic wall, with unknown aetiology and an unpredictable outcome. It has several clinical forms including porokeratosis of Mibelli, giant porokeratosis, linear porokeratosis, disseminated superficial actinic porokeratosis, palmoplantar ...
متن کاملAssociation of Porokeratosis, Vitiligo, Lichen Sclerosus et Atrophicus and Lichen Planus: A case report
Although lichen planus and vitiligo are common skin disorders, their association with two other uncommon diseases, i.e. lichen sclerosus et atrophicus and disseminated superficial actinic porokeratosis, seems to be a very rare occurrence. We report herein a 70-year-old man who developed all of these four skin disorders simultaneously.
متن کاملCoexistence of linear porokeratosis and disseminated superficial actinic porokeratosis: a type 2 segmental manifestation.
Sir, Six main clinical forms of porokeratosis are recognized: classical porokeratosis or porokeratosis of Mibelli, punctate palmoplantar porokeratosis, linear porokeratosis (LP), disseminated superficial porokeratosis, disseminated superficial actinic porokeratosis (DSAP), and disseminated palmoplantar porokeratosis (1). The coexistence of more than one form in a single individual is infrequent...
متن کامل